The Identification of Potent, Selective and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one)
Pike, Kurt G., Barlaam, Bernard, Cadogan, Elaine, Campbell, Andrew, Chen, Yingxue, Colclough, Nicola, Davies, Nichola L, DeAlmeida, Camila, Degorce, Sébastien L., Didelot, Myriam, Dishington, Allan, DLangue:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.7b01896
Date:
April, 2018
Fichier:
PDF, 1.64 MB
english, 2018
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