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Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation
van Hoppe, Stéphanie, Sparidans, Rolf W., Wagenaar, Els, Beijnen, Jos H., Schinkel, Alfred H.Volume:
120
Langue:
english
Journal:
Pharmacological Research
DOI:
10.1016/j.phrs.2017.01.035
Date:
June, 2017
Fichier:
PDF, 2.20 MB
english, 2017