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Modeling, Synthesis and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN)
Heck, Michael C, Wagner, Carl Edward, Shahani, Pritika H., MacNeill, Mairi, Grozic, Aleksandra, Darwaiz, Tamana, Shimabuku, Micah, Deans, David G, Robinson, Nathan M, Salama, Samer H, Ziller, Joseph WLangue:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/acs.jmedchem.6b00812
Date:
September, 2016
Fichier:
PDF, 2.33 MB
english, 2016