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A Mechanistic Model of the Intravitreal Pharmacokinetics of Large Molecules and the Pharmacodynamic Suppression of Ocular Vascular Endothelial Growth Factor Levels by Ranibizumab in Patients with Neovascular Age-Related Macular Degeneration
Hutton-Smith, Laurence A., Gaffney, Eamonn A., Byrne, Helen M., Maini, Philip K., Schwab, Dietmar, Mazer, Norman A.Langue:
english
Journal:
Molecular Pharmaceutics
DOI:
10.1021/acs.molpharmaceut.5b00849
Date:
January, 2016
Fichier:
PDF, 1.31 MB
english, 2016