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Hotspot Mutations in KIT Receptor Differentially Modulate Its Allosterically Coupled Conformational Dynamics: Impact on Activation and Drug Sensitivity
Chauvot de Beauchêne, Isaure, Allain, Ariane, Panel, Nicolas, Laine, Elodie, Trouvé, Alain, Dubreuil, Patrice, Tchertanov, Luba, Nilges, MichaelVolume:
10
Langue:
english
Journal:
PLoS Computational Biology
DOI:
10.1371/journal.pcbi.1003749
Date:
July, 2014
Fichier:
PDF, 3.78 MB
english, 2014