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Can In Vitro Metabolism-Dependent Covalent Binding Data in Liver Microsomes Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis of 18 Drugs with Consideration of Intrinsic Clearance and Daily Dose
Obach, R. Scott, Kalgutkar, Amit S., Soglia, John R., Zhao, Sabrina X.Volume:
21
Langue:
english
Journal:
Chemical Research in Toxicology
DOI:
10.1021/tx800161s
Date:
September, 2008
Fichier:
PDF, 403 KB
english, 2008