Discovery of 4-(5-Methyloxazolo[4,5- b ]pyridin-2-yl)-1,4-diazabicyclo[3.2.2]nonane (CP-810,123), a Novel α7 Nicotinic Acetylcholine Receptor Agonist for the Treatment of Cognitive Disorders in Schizophrenia: Synthesis, SAR Development, and in Vivo Efficacy in Cognition Models
O’Donnell, Christopher J., Rogers, Bruce N., Bronk, Brian S., Bryce, Dianne K., Coe, Jotham W., Cook, Karen K., Duplantier, Allen J., Evrard, Edelweiss, Hajós, Mihaly, Hoffmann, William E., Hurst, RaVolume:
53
Langue:
english
Journal:
Journal of Medicinal Chemistry
DOI:
10.1021/jm9015075
Date:
February, 2010
Fichier:
PDF, 1.31 MB
english, 2010