Discovery of the investigational drug TAK-441, a pyrrolo[3,2-c]pyridine derivative, as a highly potent and orally active hedgehog signaling inhibitor: Modification of the core skeleton for improved solubility
Tomohiro Ohashi, Yuya Oguro, Toshio Tanaka, Zenyu Shiokawa, Yuta Tanaka, Sachio Shibata, Yoshihiko Sato, Hiroko Yamakawa, Harumi Hattori, Yukiko Yamamoto, Shigeru Kondo, Maki Miyamoto, Mitsuhiro NishiVolume:
20
Année:
2012
Langue:
english
DOI:
10.1016/j.bmc.2012.07.034
Fichier:
PDF, 774 KB
english, 2012
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