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Articles (91)
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T1940 Molecular Characterization of An Animal Model of Oesophageal Carcinogenesis Induced By Gastro-Oesophageal Reflux in Rats: Identification of New Potential Biomarkers

Bruyère, Emilie, Briez, Nicolas, Piessen, Guillaume, Buob, David, Leteurtre, Emmanuelle, Mariette, Christophe, VAN SEUNINGEN, Isabelle

Journal:

Gastroenterology

Année:

2009

Langue:

english

Fichier:

PDF, 97 KB

english, 2009

Operatively induced chronic reflux in rats: A suitable model for studying esophageal carcinogenesis?

Gronnier, Caroline, Bruyère, Emilie, Piessen, Guillaume, Briez, Nicolas, Bot, Jérome, Buob, David, Leteurtre, Emmanuelle, Van Seuningen, Isabelle, Mariette, Christophe

Journal:

Surgery

Année:

2013

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2013

S1772 Lactobacillus GG Stimulates Mucin MUC2 Synthesis in the Human Colon Cancer Cell Line LS174T

Burger-van Paassen, Nanda, Bouma, Janneke, Boehm, Guenther, van Goudoever, Hans, VAN SEUNINGEN, Isabelle, Renes, Ingrid B

Journal:

Gastroenterology

Année:

2009

Langue:

english

Fichier:

PDF, 51 KB

english, 2009

Comment on: Functional MUC4 suppress epithelial-mesenchymal transition in lung adenocarcinoma metastasis. Gao L, Liu J, Zhang B, Zhang H, Wang D, Zhang T, Liu Y, Wang C. Tumour Biol. 2013, in press

Jonckheere, Nicolas, Van Seuningen, Isabelle

Journal:

Tumor Biology

Année:

2014

Langue:

english

Fichier:

PDF, 68 KB

english, 2014

The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells

Gronnier, Caroline, Bruyère, Emilie, Lahdaoui, Fatima, Jonckheere, Nicolas, Perrais, Michaël, Leteurtre, Emmanuelle, Piessen, Guillaume, Mariette, Christophe, Van Seuningen, Isabelle

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2014

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2014

MUC1 Expression in Papillary Thyroid Carcinoma Is Associated with BRAF Mutation and Lymph Node Metastasis; the Latter is the Most Important Risk Factor of Relapse

Renaud, Florence, Gnemmi, Viviane, Devos, Patrick, Aubert, Sébastien, Crépin, Michel, Coppin, Lucie, Ramdane, Nassima, Bouchindhomme, Brigitte, d'Herbomez, Michelle, Van Seuningen, Isabelle, Do Cao, C

Journal:

Thyroid

Année:

2014

Langue:

english

Fichier:

PDF, 277 KB

english, 2014

Description of an IL-1-Responsive Kinase That Phosphorylates the K Protein. Enhancement of Phosphorylation by Selective DNA and RNA Motifs

Van Seuningen, Isabelle, Ostrowski, Jerzy, Bomsztyk, Karol

Journal:

Biochemistry

Année:

1995

Langue:

english

Fichier:

PDF, 2.84 MB

english, 1995

Of autophagy and in vivo pancreatic carcinogenesis: The p53 status matters!

Jonckheere, Nicolas, Vincent, Audrey, Van Seuningen, Isabelle

Journal:

Clinics and Research in Hepatology and Gastroenterology

Année:

2014

Langue:

english

Fichier:

PDF, 449 KB

english, 2014

MUC5 AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer

Renaud, Florence, Vincent, Audrey, Mariette, Christophe, Crépin, Michel, Stechly, Laurence, Truant, Stéphanie, Copin, Marie-Christine, Porchet, Nicole, Leteurtre, Emmanuelle, Van Seuningen, Isabelle,

Journal:

International Journal of Cancer

Année:

2015

Langue:

english

Fichier:

PDF, 620 KB

english, 2015

The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42–44 MAPK, Akt, Bcl-2 and MMP13 pathways

Tréhoux, Solange, Duchêne, Bélinda, Jonckheere, Nicolas, Van Seuningen, Isabelle

Journal:

Biochemical and Biophysical Research Communications

Année:

2015

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2015

Mucins: a new family of epigenetic biomarkers in epithelial cancers

Van Seuningen, Isabelle, Vincent, Audrey

Journal:

Expert Opinion on Medical Diagnostics

Année:

2009

Langue:

english

Fichier:

PDF, 1.62 MB

english, 2009

Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells

Vincent, Audrey, Kazmierczak, Catherine, Duchêne, Belinda, Jonckheere, Nicolas, Leteurtre, Emmanuelle, Van Seuningen, Isabelle

Journal:

Stem Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2015

Evidence for the Tight Binding of Human Mucus Proteinase Inhibitor to Highly Glycosylated Macromolecules in Sputum

VAN-SEUNINGEN, Isabelle, DAVRIL, Monique, HAYEM, Annette

Journal:

Biological Chemistry Hoppe-Seyler

Année:

1989

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1989

Mucins and Pancreatic Cancer

Jonckheere, Nicolas, Skrypek, Nicolas, Van Seuningen, Isabelle

Journal:

Cancers

Année:

2010

Langue:

english

Fichier:

PDF, 373 KB

english, 2010

Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells

Tréhoux, Solange, Lahdaoui, Fatima, Delpu, Yannick, Renaud, Florence, Leteurtre, Emmanuelle, Torrisani, Jérôme, Jonckheere, Nicolas, Van Seuningen, Isabelle

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Année:

2015

Langue:

english

Fichier:

PDF, 2.64 MB

english, 2015

Intrauterine Growth Restriction Alters Postnatal Colonic Barrier Maturation in Rats

Fança-Berthon, Pascale, Michel, Catherine, Pagniez, Anthony, Rival, Martine, Van Seuningen, Isabelle, Darmaun, Dominique, Hoebler, Christine

Journal:

Pediatric Research

Année:

2009

Langue:

english

Fichier:

PDF, 834 KB

english, 2009

Signal Pathway of 17β-Estradiol–Induced MUC5B Expression in Human Airway Epithelial Cells

Choi, Hye Joung, Chung, Yoo-Sam, Kim, Hyun Jik, Moon, Uk Yeol, Choi, Yeon Ho, Van Seuningen, Isabelle, Baek, Seung Joon, Yoon, Ho-Geun, Yoon, Joo-Heon

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2009

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2009

The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways

Vasseur, Romain, Skrypek, Nicolas, Duchêne, Belinda, Renaud, Florence, Martínez-Maqueda, Daniel, Vincent, Audrey, Porchet, Nicole, Van Seuningen, Isabelle, Jonckheere, Nicolas

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

Année:

2015

Langue:

english

Fichier:

PDF, 2.99 MB

english, 2015

Involvement of a Signal Transduction Mechanism in ATP-induced Mucin Release from Cultured Airway Goblet Cells

Kim, K. Chul, Zheng, Qiao-Xi, Van-Seuningen, Isabelle

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

1993

Langue:

english

Fichier:

PDF, 513 KB

english, 1993

The regulation of intestinal mucin MUC2 expression by short-chain fatty acids: implications for epithelial protection

Burger-van Paassen, Nanda, Vincent, Audrey, Puiman, Patrycja J., van der Sluis, Maria, Bouma, Janneke, Boehm, Günther, van Goudoever, Johannes B., van Seuningen, Isabelle, Renes, Ingrid B.

Journal:

Biochemical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 590 KB

english, 2009

The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells

FAUQUETTE, Valérie, PERRAIS, Michael, CERULIS, Sylvain, JONCKHEERE, Nicolas, DUCOUROUBLE, Marie-Paule, AUBERT, Jean-Pierre, PIGNY, Pascal, SEUNINGEN, Isabelle Van

Journal:

Biochemical Journal

Année:

2005

Langue:

english

Fichier:

PDF, 822 KB

english, 2005

The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential

Renaud, Florence, Mariette, Christophe, Vincent, Audrey, Wacrenier, Agnès, Maunoury, Vincent, Leclerc, Julie, Coppin, Lucie, Crépin, Michel, Van Seuningen, Isabelle, Leteurtre, Emmanuelle, Buisine, Ma

Journal:

International Journal of Cancer

Année:

2016

Langue:

english

Fichier:

PDF, 847 KB

english, 2016

Suitability of Surgically Induced Chronic Reflux in Rats for Studying Esophageal Carcinogenesis

Gronnier, Caroline, Piessen, Guillaume, Leteurtre, Emmanuelle, Van Seuningen, Isabelle, Mariette, Christophe

Journal:

Annals of Surgery

Année:

2015

Langue:

english

Fichier:

PDF, 72 KB

english, 2015

Coordinated Expression of MUC2 and CDX-2 in Mucinous Carcinomas of the Lung Can Be Explained by the Role of CDX-2 as Transcriptional Regulator of MUC2

Mesquita, Patrícia, Almeida, Raquel, Van Seuningen, Isabelle, David, Leonor

Journal:

American Journal of Surgical Pathology

Année:

2004

Langue:

english

Fichier:

PDF, 302 KB

english, 2004

Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells

SEUNINGEN, Isabelle VAN, PERRAIS, Michaël, PIGNY, Pascal, PORCHET, Nicole, AUBERT, Jean-Pierre

Journal:

Biochemical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 429 KB

english, 2000

Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway

MARIETTE, Christophe, PERRAIS, Michaël, LETEURTRE, Emmanuelle, JONCKHEERE, Nicolas, HÉMON, Brigitte, PIGNY, Pascal, BATRA, Surinder, AUBERT, Jean-Pierre, TRIBOULET, Jean-Pierre, Van SEUNINGEN, Isabell

Journal:

Biochemical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 395 KB

english, 2004

Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α

Piessen, Guillaume, Jonckheere, Nicolas, Vincent, Audrey, Hémon, Brigitte, Ducourouble, Marie-Paule, Copin, Marie-Christine, Mariette, Christophe, Seuningen, Isabelle VAN

Journal:

Biochemical Journal

Année:

2007

Langue:

english

Fichier:

PDF, 1.84 MB

english, 2007

Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells

SEUNINGEN, Isabelle VAN, PERRAIS, Michaël, PIGNY, Pascal, PORCHET, Nicole, AUBERT, Jean-Pierre

Journal:

Biochemical Journal

Année:

2000

Langue:

english

Fichier:

PDF, 429 KB

english, 2000

Flagellin-mediated protection against intestinal Yersinia pseudotuberculosis infection does not require interleukin-22.

Porte, Rémi, Van Maele, Laurye, Muñoz-Wolf, Natalia, Foligné, Benoit, Dumoutier, Laure, Tabareau, Julien, Cayet, Delphine, Gosset, Pierre, Jonckheere, Nicolas, Van Seuningen, Isabelle, Chabalgoity, A.

Journal:

Infection and Immunity

Année:

2016

Langue:

english

Fichier:

PDF, 4.72 MB

english, 2016

The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting

Jonckheere, Nicolas, Vasseur, Romain, Van Seuningen, Isabelle

Journal:

Critical Reviews in Oncology/Hematology

Année:

2017

Langue:

english

Fichier:

PDF, 2.35 MB

english, 2017

Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells

Coppin, Lucie, Vincent, Audrey, Frénois, Frédéric, Duchêne, Belinda, Lahdaoui, Fatima, Stechly, Laurence, Renaud, Florence, Villenet, Céline, Seuningen, Isabelle Van, Leteurtre, Emmanuelle, Dion, Joha

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 2.80 MB

english, 2017

Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase

Gibier, Jean-Baptiste, Hémon, Brigitte, Fanchon, Mélanie, Gaudelot, Kelly, Pottier, Nicolas, Ringot, Bélinda, Van Seuningen, Isabelle, Glowacki, François, Cauffiez, Christelle, Blum, David, Copin, Mar

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Année:

2017

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2017

Lepidic predominant adenocarcinoma and invasive mucinous adenocarcinoma of the lung exhibit specific mucin expression in relation with oncogenic drivers

Michaël, Duruisseaux, Martine, Antoine, Nathalie, Rabbe, Anita, Rodenas, Anne, Mc Leer-Florin, Roger, Lacave, Virginie, Poulot, Belinda, Duchêne, Isabelle, Van Seuningen, Jacques, Cadranel, Marie, Wis

Journal:

Lung Cancer

Année:

2017

Langue:

english

Fichier:

PDF, 815 KB

english, 2017

Targeting miR-21 decreases expression of multi-drug resistant genes and promotes chemosensitivity of renal carcinoma

Gaudelot, Kelly, Gibier, Jean-Baptiste, Pottier, Nicolas, Hémon, Brigitte, Van Seuningen, Isabelle, Glowacki, François, Leroy, Xavier, Cauffiez, Christelle, Gnemmi, Viviane, Aubert, Sébastien, Perrais

Journal:

Tumor Biology

Année:

2017

Langue:

english

Fichier:

PDF, 1.60 MB

english, 2017

Transcript Profiling of Elf5+/− Mammary Glands during Pregnancy Identifies Novel Targets of Elf5

Rogers, Renee L., Van Seuningen, Isabelle, Gould, Jodee, Hertzog, Paul J., Naylor, Matthew J., Pritchard, Melanie A., Whitsett, Jeffrey A.

Journal:

PLoS ONE

Année:

2010

Langue:

english

Fichier:

PDF, 970 KB

english, 2010

Transcriptional regulation of the 11p15 mucin genes. towards new biological tools in human therapy, in inflammatory diseases and cancer?

Seuningen, Isabelle Van

Journal:

Frontiers in Bioscience

Année:

2001

Langue:

english

Fichier:

PDF, 473 KB

english, 2001

TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727

Drubay, Vincent, Skrypek, Nicolas, Cordiez, Lucie, Vasseur, Romain, Schulz, Céline, Boukrout, Nihad, Duchêne, Belinda, Coppin, Lucie, Seuningen, Isabelle Van, Jonckheere, Nicolas

Journal:

Cancers

Année:

2018

Langue:

english

Fichier:

PDF, 2.97 MB

english, 2018

Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas

Jonckheere, Nicolas, Van Seuningen, Isabelle

Journal:

Journal of Translational Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 1.70 MB

english, 2018

Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer

Neve, Bernadette, Jonckheere, Nicolas, Vincent, Audrey, Van Seuningen, Isabelle

Journal:

Cancers

Année:

2018

Langue:

english

Fichier:

PDF, 2.20 MB

english, 2018

Transcriptional regulation of the 11p15 mucin genes towards new biological tools in human therapy in inflammatory diseases and cancer

Seuningen, Isabelle Van

Journal:

Frontiers in Bioscience

Année:

2001

Fichier:

PDF, 473 KB

2001

Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival

Jonckheere, Nicolas, Auwercx, Julie, Bachir, Elsa Hadj, Coppin, Lucie, Boukrout, Nihad, Vincent, Audrey, Neve, Bernadette, Gautier, Mathieu, TreviÃ±o, Victor, Seuningen, Isabelle Van

Journal:

Cancers

Année:

2020

Fichier:

PDF, 4.64 MB

2020