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1

INDIVIDUALIZATION OF CANCER TREATMENT: CONTRIBUTION OF OMICS TECHNOLOGIES TO CANCER DIAGNOSTIC

SOUCHELNYTSKYI S.

Journal:

Biotechnologia Acta

Année:

2013

Langue:

english

Fichier:

PDF, 557 KB

english, 2013

2

Expression of Smad proteins in human colorectal cancer

Olexander Korchynskyi, Maréne Landström, Rostyslav Stoika, Keiko Funa, Carl-Henrik Heldin, Peter ten Dijke, Serhiy Souchelnytskyi

Journal:

International Journal of Cancer

Année:

1999

Langue:

english

Fichier:

PDF, 646 KB

english, 1999

3

Intracellular signaling of osteogenic protein-1 through Smad5 activation

Kiyoshi Tamaki, Serhiy Souchelnytskyi, Susumu Itoh, Atsuhito Nakao, Kuber Sampath, Carl-Henrik Heldin, Peter Ten Dijke

Journal:

Journal of Cellular Physiology

Année:

1998

Langue:

english

Fichier:

PDF, 343 KB

english, 1998

4

Increased expression of cSHMT, Tbx3 and utrophin in plasma of ovarian and breast cancer patients

Marta Lomnytska, Anna Dubrovska, Ulf Hellman, Natalya Volodko, Serhiy Souchelnytskyi

Journal:

International Journal of Cancer

Année:

2006

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2006

5

Interaction and functional cooperation between the serine/threonine kinase bone morphogenetic protein type II receptor with the tyrosine kinase stem cell factor receptor

Sylke Hassel, Mariya Yakymovych, Ulf Hellman, Lars Rönnstrand, Petra Knaus, Serhiy Souchelnytskyi

Journal:

Journal of Cellular Physiology

Année:

2006

Langue:

english

Fichier:

PDF, 450 KB

english, 2006

6

Transforming growth factor-β1-regulated proteins in human endothelial cells identified by two-dimensional gel electrophoresis and mass spectrometry

Marta Lomnytska, Vasyl Lukiyanchuk, Ulf Hellman, Serhiy Souchelnytskyi

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 201 KB

english, 2004

7

Proteins associated with type II bone morphogenetic protein receptor (BMPR-II) and identified by two-dimensional gel electrophoresis and mass spectrometry

Sylke Hassel, Annegret Eichner, Mariya Yakymovych, Ulf Hellman, Petra Knaus, Serhiy Souchelnytskyi

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 248 KB

english, 2004

8

Efficient enrichment of intact phosphorylated proteins by modified immobilized metal-affinity chromatography

Anna Dubrovska, Serhiy Souchelnytskyi

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2005

9

Bridging proteomics and systems biology: What are the roads to be traveled?

Serhiy Souchelnytskyi

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 557 KB

english, 2005

10

Glycoproteome profiling of transforming growth factor-β (TGFβ) signaling: Nonglycosylated cell death-inducing DFF-like effector A inhibits TGFβ1-dependent apoptosis

Hiroyuki Iwahana, Ihor Yakymovych, Anna Dubrovska, Ulf Hellman, Serhiy Souchelnytskyi

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 677 KB

english, 2006

11

Systemic analysis of TGFβ proteomics revealed involvement of Plag1/CNK1/RASSF1A/Src network in TGFβ1-dependent activation of Erk1/2 and cell proliferation

Nimesh Bhaskaran, Serhiy Souchelnytskyi

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 620 KB

english, 2008

12

Proteomic study of DBA/2J mice retina: Down-regulation of Integrin β7 correlated with retinal ganglion cell death

Takashi Kanamoto, Takahiro Ue, Tomoko Yokoyama, Nazariy Souchelnytskyi, Yoshiaki Kiuchi

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 235 KB

english, 2009

13

Markers of breast and gynecological malignancies: The clinical approach of proteomics-based studies

Marta Lomnytska, Serhiy Souchelnytskyi

Journal:

PROTEOMICS - Clinical Applications

Année:

2007

Langue:

english

Fichier:

PDF, 297 KB

english, 2007

14

Breast Cancer and Proteomics: The inaugural Mammary Gland Proteome Initiative (MGPI) workshop 12–13 July 2007, Cambridge, UK

Serhiy Souchelnytskyi, Louise Alldridge

Journal:

PROTEOMICS - Clinical Applications

Année:

2008

Langue:

english

Fichier:

PDF, 259 KB

english, 2008

15

Comparative proteome profiling of MCF10A and 184A1 human breast epithelial cells emphasized involvement of CDK4 and cyclin D3 in cell proliferation

Nimesh Bhaskaran, Kah Wai Lin, Aude Gautier, Hanna Woksepp, Ulf Hellman, Serhiy Souchelnytskyi

Journal:

PROTEOMICS - Clinical Applications

Année:

2009

Langue:

english

Fichier:

PDF, 741 KB

english, 2009

16

Diagnostic protein marker patterns in squamous cervical cancer

Marta I. Lomnytska, Susanne Becker, Kristina Hellman, Ann-Cathrin Hellström, Serhiy Souchelnytskyi, Miriam Mints, Ulf Hellman, Sonia Andersson, Gert Auer

Journal:

PROTEOMICS - Clinical Applications

Année:

2010

Langue:

english

Fichier:

PDF, 425 KB

english, 2010

17

Focus on Breast Cancer Proteomics

Serhiy Souchelnytskyi, Sam Hanash

Journal:

PROTEOMICS - Clinical Applications

Année:

2009

Langue:

english

Fichier:

PDF, 168 KB

english, 2009

18

Proteome profiling of immortalization-to-senescence transition of human breast epithelial cells identified MAP2K3 as a senescence-promoting protein which is downregulated in human breast cancer

Min Jia, Nazariy Souchelnytskyi, Ulf Hellman, Michael O'Hare, Parmjit S. Jat, Serhiy Souchelnytskyi

Journal:

PROTEOMICS - Clinical Applications

Année:

2010

Langue:

english

Fichier:

PDF, 509 KB

english, 2010

19

Proteome profiling of heat shock of human primary breast epithelial cells, a dataset report

Min Jia, Serhiy Souchelnytskyi

Journal:

Cell Stress and Chaperones

Année:

2011

Langue:

english

Fichier:

PDF, 630 KB

english, 2011

20

A new highly toxic protein isolated from the death cap Amanita phalloides is an l-amino acid oxidase

Taras Stasyk, Maxim Lutsik-Kordovsky, Christer Wernstedt, Volodymyr Antonyuk, Olga Klyuchivska, Serhiy Souchelnytskyi, Ulf Hellman, Rostyslav Stoika

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 564 KB

english, 2010

21

BRCA2 and Smad3 synergize in regulation of gene transcription

Preobrazhenska, Olena, Yakymovych, Mariya, Kanamoto, Takashi, Yakymovych, Ihor, Stoika, Rostyslav, Heldin, Carl-Henrik, Souchelnytskyi, Serhiy

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 253 KB

english, 2002

22

TGFβ1/Smad3 counteracts BRCA1-dependent repair of DNA damage

Dubrovska, Anna, Kanamoto, Takashi, Lomnytska, Marta, Heldin, Carl-Henrik, Volodko, Natalya, Souchelnytskyi, Serhiy

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 383 KB

english, 2005

23

Src kinase phosphorylates vascular endothelial-cadherin in response to vascular endothelial growth factor: identification of tyrosine 685 as the unique target site

Wallez, Y, Cand, F, Cruzalegui, F, Wernstedt, C, Souchelnytskyi, S, Vilgrain, I, Huber, P

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 310 KB

english, 2006

24

Novel post-translational modifications of Smad2 identified by mass spectrometry

Nimesh Bhaskaran, Hiroyuki Iwahana, Jonas Bergquist, Ulf Hellman, Serhiy Souchelnytskyi

Journal:

Central European Journal of Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.43 MB

english, 2008

25

Doxorubicin inhibits TGF-β signaling in human lung carcinoma A549 cells

Yevhen Filyak, Oksana Filyak, Serhiy Souchelnytskyi, Rostyslav Stoika

Journal:

European Journal of Pharmacology

Année:

2008

Langue:

english

Fichier:

PDF, 884 KB

english, 2008

26

TGF-β signaling from a three-dimensional perspective: insight into selection of partners

Serhiy Souchelnytskyi, Aristidis Moustakas, Carl-Henrik Heldin

Journal:

Trends in Cell Biology

Année:

2002

Langue:

english

Fichier:

PDF, 160 KB

english, 2002

27

TGFβ2 Mediates Rapid Inhibition of Calcium Influx in Identified Cholinergic Basal Forebrain Neurons

Sylvain Williams, Serhiy Souchelnytskyi, Marc Danik

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 214 KB

english, 2002

28

Bone Morphogenetic Protein-7 (OP1) and Transforming Growth Factor-β1 Modulate 1,25(OH)2-Vitamin D3-Induced Differentiation of Human Osteoblasts

Annegret Eichner, Josef Brock, Carl-Henrik Heldin, Serhiy Souchelnytskyi

Journal:

Experimental Cell Research

Année:

2002

Langue:

english

Fichier:

PDF, 779 KB

english, 2002

29

Protein tyrosine nitration in the cell cycle

Min Jia, Claudia Mateoiu, Serhiy Souchelnytskyi

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 663 KB

english, 2011

30

Smad2 suppresses the growth of Mv1Lu cells subcutaneously inoculated in mice

T. Sjöblom, I. Yakymovych, C.-H. Heldin, A. Östman, S. Souchelnytskyi

Journal:

European Journal of Cancer

Année:

2004

Langue:

english

Fichier:

PDF, 339 KB

english, 2004

31

Wnt14 inhibits death of retinal precursor cells

Mina Mizukami, Nazariy Souchelnytskyi, Yoshiaki Kiuchi, Takashi Kanamoto

Journal:

Experimental Eye Research

Année:

2009

Langue:

english

Fichier:

PDF, 576 KB

english, 2009

32

Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity

Susanne Grimsby, Hanna Jaensson, Anna Dubrovska, Marta Lomnytska, Ulf Hellman, Serhiy Souchelnytskyi

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 417 KB

english, 2004

33

The L45 loop in type I receptors for TGF-β family members is a critical determinant in specifying Smad isoform activation

Urban Persson, Hiroto Izumi, Serhiy Souchelnytskyi, Susumu Itoh, Susanne Grimsby, Ulla Engström, Carl-Henrik Heldin, Keiko Funa, Peter ten Dijke

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 286 KB

english, 1998

34

Phosphorylation of eEF1A1 at Ser300 by TβR-I Results in Inhibition of mRNA Translation

Kah Wai Lin, Ihor Yakymovych, Min Jia, Mariya Yakymovych, Serhiy Souchelnytskyi

Journal:

Current Biology

Année:

2010

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2010

35

Proteomic analyses of retina of excitatory amino acid carrier 1 deficient mice

Hideaki Okumichi, Takashi Kanamoto, Nazariy Souchelnytskyi, Seiji Tanimoto, Kohichi Tanaka, Yoshiaki Kiuchi

Journal:

Proteome Science

Année:

2007

Langue:

english

Fichier:

PDF, 753 KB

english, 2007

36

Proteome profiling of embryo chick retina

Mina Mizukami, Takashi Kanamoto, Nazariy Souchelnytskyi, Yoshiaki Kiuchi

Journal:

Proteome Science

Année:

2008

Langue:

english

Fichier:

PDF, 727 KB

english, 2008

37

Peptide Nucleic Acid (PNA)–DNA Duplexes: Comparison of Hybridization Affinity between Vertically and Horizontally Tethered PNA Probes

De, Arpita, Souchelnytskyi, Serhiy, van den Berg, Albert, Carlen, Edwin T.

Journal:

ACS Applied Materials & Interfaces

Année:

2013

Langue:

english

Fichier:

PDF, 508 KB

english, 2013

38

Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers

Attarha, S, Andersson, S, Mints, M, Souchelnytskyi, S

Journal:

British Journal of Cancer

Année:

2013

Langue:

english

Fichier:

PDF, 2.36 MB

english, 2013

39

Cancer biomarker discovery: Current status and future perspectives

Mäbert, Katrin, Cojoc, Monica, Peitzsch, Claudia, Kurth, Ina, Souchelnytskyi, Serhiy, Dubrovska, Anna

Journal:

International Journal of Radiation Biology

Année:

2014

Langue:

english

Fichier:

PDF, 698 KB

english, 2014

40

Inhibition of Transforming Growth Factor-β Signaling by Low Molecular Weight Compounds Interfering with ATP- or Substrate-Binding Sites of the TGFβ Type I Receptor Kinase †

Yakymovych, Ihor, Engström, Ulla, Grimsby, Susanne, Heldin, Carl-Henrik, Souchelnytskyi, Serhiy

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 288 KB

english, 2002

41

A Window on the Mammary Gland Proteome

Souchelnytskyi, Sam Hanash and Serhiy

Journal:

Journal of Proteome Research

Année:

2008

Langue:

english

Fichier:

PDF, 136 KB

english, 2008

42

Correction to Peptide Nucleic Acid (PNA)-DNA Duplexes: Comparison of Hybridization Affinity between Vertically and Horizontally Tethered PNA Probes

De, Arpita, Souchelnytskyi, Serhiy, van den Berg, Albert, Carlen, Edwin T.

Journal:

ACS Applied Materials & Interfaces

Année:

2013

Langue:

english

Fichier:

PDF, 215 KB

english, 2013

43

Interactome of Transforming Growth Factor-β Type I Receptor (TβRI): Inhibition of TGFβ Signaling by Epac1

Conrotto, Paolo, Yakymovych, Ihor, Yakymovych, Mariya, Souchelnytskyi, Serhiy

Journal:

Journal of Proteome Research

Année:

2007

Langue:

english

Fichier:

PDF, 884 KB

english, 2007

44

Proteomics of TGF-β signaling and its impact on breast cancer

Souchelnytskyi, Serhiy

Journal:

Expert Review of Proteomics

Année:

2005

Langue:

english

Fichier:

PDF, 483 KB

english, 2005

45

Proteomics of dedifferentiation of SK-N-BE2 neuroblastoma cells

Saini, Ravi Kanth Rao, Attarha, Sanaz, da Silva Santos, Claire, Kolakowska, Justyna, Funa, Keiko, Souchelnytskyi, Serhiy

Journal:

Biochemical and Biophysical Research Communications

Année:

2014

Langue:

english

Fichier:

PDF, 2.02 MB

english, 2014

46

ИНДИВИДУАЛЬНЫЙ ПОДХОД В ЛЕЧЕНИИ РАКА: ВКЛАД OMIC-ТЕХНОЛОГИЙ В ДИАГНОСТИКУ ЗАБОЛЕВАНИЯ

SOUCHELNYTSKYI S.

Journal:

Biotechnologia Acta

Année:

2013

Langue:

english

Fichier:

PDF, 557 KB

english, 2013

47

Proteome Profiling of Human Cutaneous Leishmaniasis Lesion

da Silva Santos, Claire, Attarha, Sanaz, Saini, Ravi Kanth, Boaventura, Viviane, Costa, Jackson, Khouri, Ricardo, Barral-Netto, Manoel, Brodskyn, Cláudia Ida, Souchelnytskyi, Serhiy

Journal:

The Journal of Investigative Dermatology

Année:

2015

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2015

48

Smad2 Phosphorylation by Type I Receptor: CONTRIBUTION OF ARGININE 462 AND CYSTEINE 463 IN THE C TERMINUS OF SMAD2 FOR SPECIFICITY

Yakymovych, I., Heldin, C.-H., Souchelnytskyi, S.

Journal:

Journal of Biological Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 1010 KB

english, 2004

49

Phosphorylation of Serine 11 and Serine 92 as New Positive Regulators of Human Snail1 Function: Potential Involvement of Casein Kinase-2 and the cAMP-activated Kinase Protein Kinase A

MacPherson, M. R., Molina, P., Souchelnytskyi, S., Wernstedt, C., Martin-Perez, J., Portillo, F., Cano, A.

Journal:

Molecular Biology of the Cell

Année:

2010

Langue:

english

Fichier:

PDF, 1.81 MB

english, 2010

50

Quantitative intact proteomics investigations of alveolar macrophages in sarcoidosis

Silva, Ernesto, Souchelnytskyi, Serhiy, Kasuga, Kie, Eklund, Anders, Grunewald, Johan, Wheelock, Åsa M.

Journal:

European Respiratory Journal

Année:

2013

Langue:

english

Fichier:

PDF, 721 KB

english, 2013