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51

Effect of methylglyoxal on the physico-chemical and biological properties of low-density lipoprotein

Schalkwijk, Casper G., Vermeer, Mario A., Stehouwer, Coen D.A., te Koppele, Johan, Princen, Hans M.G., van Hinsbergh, Victor W.M.

Journal:

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism

Année:

1998

Langue:

english

Fichier:

PDF, 239 KB

english, 1998

52

Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat

Hoekman, Marco F.M., Rientjes, Jeanet M.J., Twisk, Jaap, Planta, Rudi J., Princen, Hans M.G., Mager, Willem H.

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 165 KB

english, 1994

53

Plasma coenzyme Q 10 concentrations are not decreased in male patients with coronary atherosclerosis

van de Vijver, Lucy P.L., Weber, Christine, Kardinaal, Alwine F.M., Grobbee, Diederick E., Princen, Hans M.G., van Poppel, Geert

Journal:

Free Radical Research

Année:

1999

Langue:

english

Fichier:

PDF, 671 KB

english, 1999

54

Antioxidants and Coronary Heart Disease

Poppel, Geert van, Kardinaal, Alwine, Princen, Hans, Kok, Frans J.

Journal:

Annals of Medicine

Année:

1994

Langue:

english

Fichier:

PDF, 624 KB

english, 1994

55

No effects of atorvastatin (10mg/d or 80mg/d) on nitric oxide, prostacyclin, thromboxane and oxidative stress in type 2 diabetes mellitus patients of the DALI study

Tsikas, Dimitrios, Pham, Vu Vi, Suchy, Maria-Theresia, van de Ree, Marcel A., Huisman, Menno V., Frölich, Jürgen C., Princen, Hans M.G.

Journal:

Pharmacological Research

Année:

2015

Langue:

english

Fichier:

PDF, 870 KB

english, 2015

56

Innovative pharmaceutical interventions in cardiovascular disease: Focusing on the contribution of non-HDL-C/LDL-C-lowering versus HDL-C-raisingA systematic review and meta-analysis of relevant preclinical studies and clinical trials

Kühnast, Susan, Fiocco, Marta, van der Hoorn, José W.A., Princen, Hans M.G., Jukema, J. Wouter

Journal:

European Journal of Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 986 KB

english, 2015

57

Bexarotene Induces Dyslipidemia by Increased Very Low-Density Lipoprotein Production and Cholesteryl Ester Transfer Protein-Mediated Reduction of High-Density Lipoprotein

de Vries-van der Weij, Jitske, de Haan, Willeke, Hu, Lihui, Kuif, Maarten, Oei, H. Ling D. W., van der Hoorn, José W. A., Havekes, Louis M., Princen, Hans M. G., Romijn, Johannes A., Smit, Johannes W.

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 236 KB

english, 2009

58

The Cholesterol-Raising Factor from Coffee Beans, Cafestol, as an Agonist Ligand for the Farnesoid and Pregnane X Receptors

Ricketts, Marie-Louise, Boekschoten, Mark V., Kreeft, Arja J., Hooiveld, Guido J. E. J., Moen, Corina J. A., Müller, Michael, Frants, Rune R., Kasanmoentalib, Soemini, Post, Sabine M., Princen, Hans M

Journal:

Molecular Endocrinology

Année:

2007

Fichier:

PDF, 491 KB

2007

59

The Cholesterol-Raising Factor from Coffee Beans, Cafestol, as an Agonist Ligand for the Farnesoid and Pregnane X Receptors

Ricketts, Marie-Louise, Boekschoten, Mark V., Kreeft, Arja J., Hooiveld, Guido J. E. J., Moen, Corina J. A., Müller, Michael, Frants, Rune R., Kasanmoentalib, Soemini, Post, Sabine M., Princen, Hans M

Journal:

Molecular Endocrinology

Année:

2007

Langue:

english

Fichier:

PDF, 491 KB

english, 2007

60

Oxidation of LDL and extent of peripheral atherosclerosis

van de Vijver, Lucy P.L., Kardinaal, Alwine F.M., van Duyvenvoorde, Wim, Kruijssen, Dick A.C.M., Grobbee, Diederick E., van Poppel, Geert, Princen, Hans M.G.

Journal:

Free Radical Research

Année:

1999

Langue:

english

Fichier:

PDF, 1.09 MB

english, 1999

61

Anti-Atherosclerotic Effect of Amlodipine, Alone and in Combination With Atorvastatin, in APOE*3-Leiden/hCRP Transgenic Mice

Trion, Astrid, de Maat, Moniek, Jukema, Wouter, Maas, Annemarie, Offerman, Erik, Havekes, Louis, Szalai, Alex, Laarse, Arnoud van der, Princen, Hans, Emeis, Jef

Journal:

Journal of Cardiovascular Pharmacology

Année:

2006

Langue:

english

Fichier:

PDF, 430 KB

english, 2006

62

Genetic Analysis of Indicators of Cholesterol Synthesis and Absorption: Lathosterol and Phytosterols in Dutch Twins and Their Parents

Boomsma, Dorret I., Princen, Hans M., Frants, Rune R., Gevers Leuven, Jan A., Kempen, Herman-Jan M.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 108 KB

english, 2003

63

Differential Effects of Amlodipine and Atorvastatin Treatment and Their Combination on Atherosclerosis in ApoE*3-Leiden Transgenic Mice

Delsing, Dianne J. M., Jukema, Wouter J., van de Wiel, Mark A., Emeis, Jef J., van der Laarse, Arnoud, Havekes, Louis M., Princen, Hans M. G.

Journal:

Journal of Cardiovascular Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 638 KB

english, 2003

64

Comment on “Hypercholesterolemia with consumption of PFOA-laced Western diets is dependent on strain and sex of mice” by Rebholz S.L. et al. Toxicol. Rep. 2016 (3) 46–54

Princen, Hans M.G., Pouwer, Marianne G., Pieterman, Elsbet J.

Journal:

Toxicology Reports

Année:

2016

Langue:

english

Fichier:

PDF, 829 KB

english, 2016

65

Negative effects of rofecoxib treatment on cardiac function after ischemia-reperfusion injury in APOE3Leiden mice are prevented by combined treatment with thromboxane prostanoid-receptor antagonist S18886 (terutroban)

van der Hoorn, José W., Jukema, J Wouter, Bekkers, Marian E., Princen, Hans M., Corda, Stefano, Emeis, Jeff J., Steendijk, Paul

Journal:

Critical Care Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 978 KB

english, 2008

66

Salsalate attenuates diet induced non-alcoholic steatohepatitis in mice by decreasing lipogenic and inflammatory processes

Liang, Wen, Verschuren, Lars, Mulder, Petra, van der Hoorn, José W.A., Verheij, Joanne, van Dam, Andrea D., Boon, Mariette R., Princen, Hans M.G., Havekes, Louis M., Kleemann, Robert, van den Hoek, An

Journal:

British Journal of Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 4.47 MB

english, 2015

67

Olmesartan and pravastatin additively reduce development of atherosclerosis in APOE*3Leiden transgenic mice

van der Hoorn, José WA, Kleemann, Robert, Havekes, Louis M, Kooistra, Teake, Princen, Hans MG, Jukema, J Wouter

Journal:

Journal of Hypertension

Année:

2007

Langue:

english

Fichier:

PDF, 244 KB

english, 2007

68

Aliskiren inhibits atherosclerosis development and improves plaque stability in APOE*3Leiden.CETP transgenic mice with or without treatment with atorvastatin

Kühnast, Susan, van der Hoorn, José W.A., van den Hoek, Anita M., Havekes, Louis M., Liau, Gene, Jukema, J. Wouter, Princen, Hans M.G.

Journal:

Journal of Hypertension

Année:

2012

Langue:

english

Fichier:

PDF, 556 KB

english, 2012

69

Genetic Analysis of Indicators of Cholesterol Synthesis and Absorption: Lathosterol and Phytosterols in Dutch Twins and Their Parents

Boomsma, Dorret I., Princen, Hans M., Frants, Rune R., Gevers Leuven, Jan A., Kempen, Herman-Jan M.

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 187 KB

english, 2003

70

Serum Carotenoids and Vitamins in Relation to Markers of Endothelial Function and Inflammation

Wendy M. R. van Herpen-Broekmans, Ineke A. A. Klöpping-Ketelaars , Michiel L. Bots, Cornelis Kluft, Hans Princen, Henk F. J. Hendriks, Lilian B. M. Tijburg, Geert van Poppel and Alwine F. M. Kardinaal

Journal:

European Journal of Epidemiology

Année:

2004

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2004

71

Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7α-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes

POST, Sabine M., TWISK, Jaap, VAN DER FITS, Leslie, DE WIT, Elly C.M., HOEKMAN, Marco F.M., MAGER, Willem H., PRINCEN, Hans M.G.

Journal:

Biochemical Journal

Année:

1999

Langue:

english

Fichier:

PDF, 153 KB

english, 1999

72

Lipoprotein cholesterol uptake mediates up-regulation of bile-acid synthesis by increasing cholesterol 7α-hydroxylase but not sterol 27-hydroxylase gene expression in cultured rat hepatocytes

POST, Sabine M., TWISK, Jaap, FITS, L V D, WIT, Elly C. M. DE, HOEKMAN, Marco F. M., MAGER, Willem H., PRINCEN, Hans M. G.

Journal:

Biochemical Journal

Année:

1999

Langue:

english

Fichier:

PDF, 153 KB

english, 1999

73

Regulation of cholesterol metabolism in the liver in vivo and in vitro

COHEN, LOUIS H., PRINCEN, HANS M. G., KWEKKEBOOM, JAAP, HAVEKES, LOUS M., KEMPEN, JAN HERMAN

Journal:

Biochemical Society Transactions

Année:

1987

Langue:

english

Fichier:

PDF, 364 KB

english, 1987

74

Bile acid synthesis by human hepatoma cell line Hep-G2 is stimulated by low density lipoprotein

KEMPEN, HERMAN JAN, LOMMERSE, ELLEN, VAN SCHIE, RINA, HEPP, ELLEN, MEYER, PIET, PRINCEN, HANS

Journal:

Biochemical Society Transactions

Année:

1988

Langue:

english

Fichier:

PDF, 277 KB

english, 1988

75

Genetic variation in the rate-limiting enzyme in cholesterol catabolism (cholesterol 7α-hydroxylase) influences the progression of atherosclerosis and risk of new clinical events

HOFMAN, Maaike K., PRINCEN, Hans M. G., ZWINDERMAN, Aeilko H., JUKEMA, J. Wouter

Journal:

Clinical Science

Année:

2005

Langue:

english

Fichier:

PDF, 163 KB

english, 2005

76

Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase

Simic, Branko, Mocharla, Pavani, Crucet, Margot, Osto, Elena, Kratzer, Adelheid, Stivala, Simona, Kühnast, Susan, Speer, Thimoteus, Doycheva, Petia, Princen, Hans M., van der Hoorn, Jose W., Jukema, J

Journal:

Atherosclerosis

Année:

2017

Langue:

english

Fichier:

PDF, 830 KB

english, 2017

77

The AT04A vaccine against proprotein convertase subtilisin/kexin type 9 reduces total cholesterol, vascular inflammation, and atherosclerosis in APOE*3Leiden.CETP mice

Landlinger, Christine, Pouwer, Marianne G., Juno, Claudia, van der Hoorn, José W.A., Pieterman, Elsbet J., Jukema, J. Wouter, Staffler, Guenther, Princen, Hans M.G., Galabova, Gergana

Journal:

European Heart Journal

Année:

2017

Langue:

english

Fichier:

PDF, 913 KB

english, 2017

78

Cardiovascular safety of BCR-ABL1 tyrosine kinase inhibitors: imatinib and ponatinib decrease plasma cholesterol and atherosclerosis in APOE3*Leiden.CETP Mice

Pouwer, Marianne, Pieterman, Elsbet, Verschuren, Lars, Caspers, Martien, Kluft, Kees, Garcia, Ricardo, Lee, Frank, Aman, Jurjan, Jukema, Wouter, Princen, Hans

Journal:

Atherosclerosis

Année:

2017

Langue:

english

Fichier:

PDF, 143 KB

english, 2017

79

Atorvastatin accelerates clearance of lipoprotein remnants generated by activated brown fat to further reduce hypercholesterolemia and atherosclerosis

Hoeke, Geerte, Wang, Yanan, van Dam, Andrea D., Mol, Isabel M., Gart, Eveline, Klop, Henk G., van den Berg, Susan M., Pieterman, Elsbet H., Princen, Hans M.G., Groen, Albert K., Rensen, Patrick C.N.,

Journal:

Atherosclerosis

Année:

2017

Langue:

english

Fichier:

PDF, 2.54 MB

english, 2017

80

Results, meta-analysis and a first evaluation of UNOxR, the urinary nitrate-to-nitrite molar ratio, as a measure of nitrite reabsorption in experimental and clinical settings

Tsikas, Dimitrios, Hanff, Erik, Bollenbach, Alexander, Kruger, Ruan, Pham, Vu Vi, Chobanyan-Jürgens, Kristine, Wedekind, Dirk, Arndt, Tanja, Jörns, Anne, Berbée, Jimmy F. P., Princen, Hans M. G., Lück

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2018

81

Effect of garlic powder on C-reactive protein and plasma lipids in overweight and smoking subjects

van Doorn, Martijn BA, Santo, Sonia M Espirito, Meijer, Piet, Kamerling, Ingrid M, Schoemaker, Rik C, Dirsch, Verena, Vollmar, Angelika, Haffner, Thomas, Gebhardt, Rolf, Cohen, Adam F, Princen, Hans M

Journal:

American Journal of Clinical Nutrition

Année:

2006

Langue:

english

Fichier:

PDF, 64 KB

english, 2006

82

Elafibranor Reverses Nonalcoholic Steatohepatitis and Blocks Progression of Fibrosis in APOE*3.Leiden.CETP Mice

Pouwer, Marianne G., Jukema, J.W., Princen, Hans M., van den Hoek, Anita M.

Journal:

Atherosclerosis Supplements

Année:

2018

Langue:

english

Fichier:

PDF, 62 KB

english, 2018

83

Inflammatory Cytokine Oncostatin M Induces Endothelial Activation in vitro and in APOE*3Leiden.CETP Mice

van Keulen, Danielle, Pouwer, Marianne G., Pasterkamp, Gerard, van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M., Tempel, Dennie

Journal:

Atherosclerosis Supplements

Année:

2018

Langue:

english

Fichier:

PDF, 50 KB

english, 2018

84

The BCR-ABL1 Inhibitors Imatinib and Ponatinib Decrease Plasma Cholesterol and Atherosclerosis, and Nilotinib and Ponatinib Activate Coagulation in a Translational Mouse Model

Pouwer, Marianne G., Pieterman, Elsbet J., Verschuren, Lars, Caspers, Martien P. M., Kluft, Cornelis, Garcia, Ricardo A., Aman, Jurjan, Jukema, J. Wouter, Princen, Hans M. G.

Journal:

Frontiers in Cardiovascular Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 2.38 MB

english, 2018

85

Fish Oil Increases Bile Acid Synthesis in Male Patients with Hypertriglyceridemia

Jonkers, Iris J. A. M., Smelt, Augustinus H. M., Princen, Hans M. G., Kuipers, Folkert, Romijn, Johannes A., Boverhof, Renze, Masclee, Ad A. M., Stellaard, Frans

Journal:

Journal of Nutrition

Année:

2006

Langue:

english

Fichier:

PDF, 100 KB

english, 2006

86

Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE*3Leiden.CETP mice

van Keulen, Danielle, Pouwer, Marianne G., Pasterkamp, Gerard, van Gool, Alain J., Sollewijn Gelpke, Maarten D., Princen, Hans M. G., Tempel, Dennie, Bader, Michael

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 6.26 MB

english, 2018

87

Well-Characterized Garlic-Derived Materials Are Not Hypolipidemic in APOE*3-Leiden Transgenic Mice

Espirito Santo, Sonia M. S., van Vlijmen, Bart J. M., Buytenhek, Rien, van Duyvenvoorde, Wim, Havekes, Louis M., Arnault, Ingrid, Auger, Jacques, Princen, Hans M. G.

Journal:

Journal of Nutrition

Année:

2004

Langue:

english

Fichier:

PDF, 160 KB

english, 2004

88

CYP7A1 A-278C Polymorphism Affects the Response of Plasma Lipids after Dietary Cholesterol or Cafestol Interventions in Humans

Hofman, Maaike K., Weggemans, Rianne M., Zock, Peter L., Schouten, Evert G., Katan, Martijn B., Princen, Hans M. G.

Journal:

Journal of Nutrition

Année:

2004

Fichier:

PDF, 107 KB

2004

89

CYP7A1 A-278C Polymorphism Affects the Response of Plasma Lipids after Dietary Cholesterol or Cafestol Interventions in Humans

Hofman, Maaike K., Weggemans, Rianne M., Zock, Peter L., Schouten, Evert G., Katan, Martijn B., Princen, Hans M. G.

Journal:

Journal of Nutrition

Année:

2004

Langue:

english

Fichier:

PDF, 107 KB

english, 2004

90

Anti-PCSK9 antibodies inhibit pro-atherogenic mechanisms in APOE*3Leiden.CETP mice

Schuster, Susanne, Rubil, Sandra, Endres, Matthias, Princen, Hans M. G., Boeckel, Jes-Niels, Winter, Karsten, Werner, Christian, Laufs, Ulrich

Journal:

Scientific Reports

Année:

2019

Langue:

english

Fichier:

PDF, 4.33 MB

english, 2019

91

Supplementation With Low Doses of Vitamin E Protects LDL From Lipid Peroxidation in Men and Women

Princen, Hans M.G., van Duyvenvoorde, Wim, Buytenhek, Rien, van der Laarse, Arnoud, van Poppel, Geert, Leuven, Jan A. Gevers, van Hinsbergh, Victor W.M.

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

1995

Fichier:

PDF, 1.27 MB

1995

92

Alirocumab, evinacumab, and atorvastatin triple therapy regresses plaque lesions and improves lesion composition in mice

Pouwer, Marianne G, Pieterman, Elsbet J., Worms, Nicole, Keijzer, Nanda, Jukema, J. Wouter, Gromada, Jesper, Gusarova, Viktoria, Princen, Hans M.G.

Journal:

The Journal of Lipid Research

Année:

2019

Fichier:

PDF, 1.88 MB

2019

93

Icosabutate Exerts Beneficial Effects Upon Insulin Sensitivity, Hepatic Inflammation, Lipotoxicity, and Fibrosis in Mice

Hoek, Anita M., Pieterman, Elsbet J., Hoorn, José W., Iruarrizaga‐Lejarreta, Marta, Alonso, Cristina, Verschuren, Lars, Skjæret, Tore, Princen, Hans M.G., Fraser, David A.

Journal:

Hepatology Communications

Année:

2019

Fichier:

PDF, 1.56 MB

2019

94

Effects of Simvastatin on Plasma Lipids and Apolipoproteins in Familial Hypercholesterolemic Swine

Hasler-Rapacz, Judith, Kempen, Herman J., Princen, Hans M.G., Kudchodkar, Bhalchandra J., Lacko, Andras, Rapacz, Jan

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

1996

Langue:

english

Fichier:

PDF, 712 KB

english, 1996

95

Fibrates Suppress Fibrinogen Gene Expression in Rodents Via Activation of the Peroxisome Proliferator-Activated Receptor-î

Kockx, Maaike, Gervois, Philippe P., Poulain, Philippe, Derudas, Bruno, Peters, Jeffrey M., Gonzalez, Frank J., Princen, Hans M.G., Kooistra, Teake, Staels, Bart

Journal:

Année:

1999

Fichier:

PDF, 250 KB

1999

96

Effects of Inhibition or Deletion of PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) on Intracerebral Hemorrhage Volumes in Mice

Schlunk, Frieder, Fischer, Paul, Princen, Hans M.G., Rex, Andre, Prinz, Vincent, Foddis, Marco, LÃ¼tjohann, Dieter, Laufs, Ulrich, Endres, Matthias

Journal:

Année:

2020

Fichier:

PDF, 132 KB

2020

97

[BMJ Publishing Group Ltd and European League Against Rheumatism Annual European Congress of Rheumatology, EULAR 2019, Madrid, 12â15 June 2019 - ()] Cartilage, synovium and bone - FRI0528âHIGH INTENSIVE THERAPEUTIC LOWERING OF SYSTEMIC CHOLESTEROL DOES NOT AMELIORATE OA DEVELOPMENT IN KNEE JOINTS OF HUMANIZED DYSLIPIDEMIC MICE

Gemert, Yvonne van, Kozijn, Anne, Pouwer, Marianne, Kruisbergen, Nik, Bosch, Martijn van den, Blom, Arjen, Pieterman, Elsbeth, Weinans, Harrie, Stoop, Reinout, Princen, Hans, Lent, Peter van

Année:

2019

Fichier:

PDF, 68 KB

2019