Lawler, Sean E. : rechercher sur Z-Library

Le plus grand référentiel d'articles scientifiques au monde. 70,000,000+ d'articles gratuitement.

Don't use scam websites

Livres
Articles (120)
Les plus populaires
Liste
- Liste
- Tableau

51

Genomic and Personalized Medicine || Brain Tumors and Gliomas

Lawler, Sean E.

Année:

2013

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2013

52

Physiological Transgene Regulation and Functional Complementation of a Neurological Disease Gene Deficiency in Neurons

Peruzzi, Pier Paolo, Lawler, Sean E, Senior, Steve L, Dmitrieva, Nina, Edser, Pauline AH, Gianni, Davide, Chiocca, E Antonio, Wade-Martins, Richard

Journal:

Molecular Therapy

Année:

2009

Langue:

english

Fichier:

PDF, 505 KB

english, 2009

53

Quantitative Analysis of Complex Glioma Cell Migration on Electrospun Polycaprolactone Using Time-Lapse Microscopy

Johnson, Jed, Nowicki, M. Oskar, Lee, Carol H., Chiocca, E. Antonio, Viapiano, Mariano S., Lawler, Sean E., Lannutti, John J.

Journal:

Tissue Engineering Part C Methods

Année:

2009

Langue:

english

Fichier:

PDF, 41.02 MB

english, 2009

54

Targeting Glioblastoma Invasion with GSK-3 inhibitors: Rapid Effects on the EMT Marker Vimentin

Nowicki, Michal O., Chiocca, E. Antonio, Lawler, Sean E.

Journal:

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques

Année:

2014

Langue:

english

Fichier:

PDF, 508 KB

english, 2014

55

IMPS-21EFFECT OF rQNestin 34.5 ONCOLYTIC HERPES VIRUS ON IMMUNE CHECKPOINT GENE EXPRESSION IN GLIOBLASTOMA CELLS AND EVALUATION OF THERAPEUTIC EFFICACY

Speranza, Maria-Carmela, Kasai, Kazue, Kaufmann, Johanna, Nakashima, Hiroshi, Lawler, Sean, Chiocca, E. Antonio

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 26 KB

english, 2015

56

GENO-17AN 8-microRNA SIGNATURE PREDICTS RESPONSE TO BEVACIZUMAB IN GLIOBLASTOMA

Hayes, Josie, French, Pim, Van Den Bent, Martin, Gregory, Walter, Westhead, David, Lawler, Sean, Short, Susan

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 26 KB

english, 2015

57

ATPS-48A HIGH-THROUGHPUT SCREEN IDENTIFIES microRNA-1300 AS A POTENTIAL THERAPEUTIC microRNA CAUSING CYTOKINESIS FAILURE AND APOPTOSIS IN GLIOBLASTOMA CELLS

Boissinot, Marjorie, Adams, Matthew, Higgins, Julie, King, Henry, Steele, Lynette, Morton, Ruth, Hayes, Josie, Droop, Alastair, Bond, Jacqueline, Tomlinson, Darren, Short, Susan, Lawler, Sean

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 25 KB

english, 2015

58

Preclinical Mouse Models for Analysis of the Therapeutic Potential of Engineered Oncolytic Herpes Viruses

Speranza, Maria-Carmela, Kasai, Kazue, Lawler, Sean E.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 245 KB

english, 2016

59

Design of a microfluidic chip for magnetic-activated sorting of one-bead-one-compound libraries

Cho, Choi-Fong, Lee, Kyungheon, Speranza, Maria-Carmela, Bononi, Fernanda C, Viapiano, Mariano Sebastian, Luyt, Leonard G., Weissleder, Ralph, Chiocca, E. Antonio, Lee, Hakho, Lawler, Sean Edward

Journal:

ACS Combinatorial Science

Année:

2016

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2016

60

ATPS-08DISCOVERY OF NOVEL GLIOMA-TARGETING PEPTIDES USING A HIGH-THROUGHPUT MICROFLUIDIC MAGNETIC-ACTIVATED SORTER

Cho, Choi-Fong, Bononi, Fernanda, Wolfe, Justin, Pentelute, Bradley, Luyt, Leonard, Viapiano, Mariano, Chiocca, E. Antonio, Lawler, Sean

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 26 KB

english, 2015

61

Sorting Out Mix-Ups: The Provenance of Tissue Sections May Be Confirmed by PCR Using Microsatellite Markers

Sean O’Briain, D., Sheils, Orla, McElwaine, Suzanne, McCann, Shaun R., Lawler, Mark

Journal:

American Journal of Clinical Pathology

Année:

1996

Langue:

english

Fichier:

PDF, 1.34 MB

english, 1996

62

MicroRNA Functions and Potential Clinical Utility in Glioblastoma

E. Lawler, Sean

Journal:

Current Signal Transduction Therapy

Année:

2013

Langue:

english

Fichier:

PDF, 295 KB

english, 2013

63

Oncolytic Viruses in Cancer Treatment

Lawler, Sean E., Speranza, Maria-Carmela, Cho, Choi-Fong, Chiocca, E. Antonio

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 297 KB

english, 2016

64

Highlights from the Literature

Lawler, Sean, Schiff, David, Wick, Wolfgang, Chamberlain, Marc, Wright, Karen

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 68 KB

english, 2016

65

A validated microRNA profile with predictive potential in glioblastoma patients treated with bevacizumab

Hayes, Josie, Thygesen, Helene, Gregory, Walter, Westhead, David R., French, Pim J., Van Den Bent, Martin J., Lawler, Sean E., Short, Susan C.

Journal:

Molecular Oncology

Année:

2016

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2016

66

Construction of an Escherichia coli secretion vector for a human proinsulin analogue

LAWLER, SEAN E., PITTS, JAMES E.

Journal:

Biochemical Society Transactions

Année:

1989

Langue:

english

Fichier:

PDF, 406 KB

english, 1989

67

Secretion of a chymosin-insulin fusion in Trichoderma reesei

LAWLER, SEAN E., PITTS, JIM E., MANTAFOUNIS, DIMITRIS, GILL, RAJ, UUSITALO, JANNA, PENTTILÄ, MERJA

Journal:

Biochemical Society Transactions

Année:

1991

Langue:

english

Fichier:

PDF, 128 KB

english, 1991

68

Protein engineering of the surface loops of chymosin

ORPRAYOON, POONSOOK, PITTS, JIM E., NUGENT, PHILIP, MANTAFOUNIS, DIMITRIS, LAWLER, SEAN E., BLUNDELL, TOM L., UUSITALO, JANNA, PENTTILÄ, MERJA

Journal:

Biochemical Society Transactions

Année:

1991

Langue:

english

Fichier:

PDF, 105 KB

english, 1991

69

Modifying the substrate specificity of chymosin

QUINN, DOMINIC, PITTS, JIM E., MANTAFOUNIS, DIMITRIS, LAWLER, SEAN E., UUSITALO, JANNA, PENTTILÄ, MERJA, STROP, PETER

Journal:

Biochemical Society Transactions

Année:

1991

Langue:

english

Fichier:

PDF, 106 KB

english, 1991

70

Regulation of Th1/Th2 cells in asthma development: A mathematical model

Hwang, Hyung Ju, Kim, Yoon-Keun, Gho, Yong Song, Lawler, Sean, Kim, You-Sun, Lee, Seongwon, Kim, Yangjin

Journal:

Mathematical Biosciences and Engineering

Année:

2013

Langue:

english

Fichier:

PDF, 1.69 MB

english, 2013

71

Developing Quality Measures for Sepsis Care in the ICU

Berenholtz, Sean M., Pronovost, Peter J., Ngo, Koni, Barie, Philip S., Hitt, John, Kuti, Joseph L., Septimus, Edward, Lawler, Nancy, Schilling, Lisa, Dorman, Todd

Journal:

The Joint Commission Journal on Quality and Patient Safety

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

72

IMST-21. GLIOBLASTOMA-DERIVED EXTRACELLULAR VESICLES DYNAMICALLY CARRY PDL1 AND SPECIFICALLY INHIBIT CD4+ AND CD8+ T-CELL ACTIVATION AND PROLIFERATION

Ricklefs, Franz, Speranza, Maria Carmela, Lee, Kyungheon, Passaro, Carmela, Lee, Hakho, Weissleder, Ralph, Bronisz, Agnieszka, Lawler, Sean E., Chiocca, E. Antonio

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 48 KB

english, 2016

73

BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma

Speranza, Maria-Carmela, Nowicki, Michal O., Behera, Prajna, Cho, Choi-Fong, Chiocca, E. Antonio, Lawler, Sean E.

Journal:

Scientific Reports

Année:

2016

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2016

74

The brain microenvironment negatively regulates miRNA-768-3p to promote K-ras expression and lung cancer metastasis

Subramani, Arasukumar, Alsidawi, Samer, Jagannathan, Sajjeev, Sumita, Kazutaka, Sasaki, Atsuo T., Aronow, Bruce, Warnick, Ronald E., Lawler, Sean, Driscoll, James J.

Journal:

Scientific Reports

Année:

2013

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2013

75

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

Cho, Choi-Fong, Wolfe, Justin M., Fadzen, Colin M., Calligaris, David, Hornburg, Kalvis, Chiocca, E. Antonio, Agar, Nathalie Y. R., Pentelute, Bradley L., Lawler, Sean E.

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 2.81 MB

english, 2017

76

Highlights from the Literature

Purow, Benjamin, Gerstner, Elizabeth, Lawler, Sean, Wright, Karen, Viapiano, Mariano

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 66 KB

english, 2017

77

Bi-specific molecule against EGFR and death receptors simultaneously targets proliferation and death pathways in tumors

Zhu, Yanni, Bassoff, Nicole, Reinshagen, Clemens, Bhere, Deepak, Nowicki, Michal O., Lawler, Sean E., Roux, Jérémie, Shah, Khalid

Journal:

Scientific Reports

Année:

2017

Langue:

english

Fichier:

PDF, 4.90 MB

english, 2017

78

Selective BCL-XL inhibition promotes apoptosis in combination with MLN8237 in medulloblastoma and pediatric glioblastoma cells

Levesley, Jane, Steele, Lynette, Brüning-Richardson, Anke, Davison, Adam, Zhou, Jia, Ding, Chunyong, Lawler, Sean, Short, Susan C.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2017

79

EXTH-51. BREVICAN-SPECIFIC PEPTIDES FOR THE DEVELOPMENT OF NEXT-GENERATION TARGETED THERANOSTICS FOR MALIGNANT GLIOMAS

Cho, Choi-Fong, Kasai, Kazue, Wolfe, Justin, Hornburg, Kalvis, Bononi, Fernanda, Luyt, Leonard, Pentelute, Bradley, Viapiano, Mariano, Chiocca, E. Antonio, Lawler, Sean E.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 50 KB

english, 2016

80

Shifting the balance of power? The combination of oncolytic virotherapy and immune checkpoint blockade for glioblastoma treatment

Lawler, Sean E.

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 845 KB

english, 2017

81

Erratum: USP11 regulates PML stability to control Notch-induced malignancy in brain tumours

Wu, Hsin-Chieh, Lin, Yu-Ching, Liu, Cheng-Hsin, Chung, Hsiang-Ching, Wang, Ya-Ting, Lin, Ya-Wen, Ma, Hsin-I., Tu, Pang-Hsien, Lawler, Sean E., Chen, Ruey-Hwa

Journal:

Nature Communications

Année:

2017

Langue:

english

Fichier:

PDF, 571 KB

english, 2017

82

Highlights from the Literature

Huse, Jason, Wick, Wolfgang, Lawler, Sean, Abounader, Roger, Schiff, David, Aldape, Kenneth

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 62 KB

english, 2018

83

DDIS-19. NOVEL PEPTIDE HOMING TO GLIOMA-SPECIFIC ISOFORM OF BREVICAN SELECTIVELY TARGETS MALIGNANT BRAIN TUMORS

Cho, Choi-Fong, Ghotmi, Yarah, Fazden, Colin, Wolfe, Justin, Bononi, Fernanda, Murrell, Emily, Luyt, Leonard, Viapiano, Mariano, Pentelute, Bradley, Chiocca, E Antonio, Lawler, Sean E

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 93 KB

english, 2017

84

Identification of transcriptional targets of GSK3 involved in glioblastoma invasion

Bruning-Richardson, Anke, Droop, Alastair, Tams, Dan, Boissinot, Marjorie, Hayes, Josie, Cheng, Vinton, Cockle, Julia, Ismail, Azzam, Morton, Ruth, Esteves, Filomena, Mittelbronn, Michel, Lawler, Sean

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 34 KB

english, 2018

85

Highlights from the Literature

Gerstner, Elizabeth, Hegi, Monika, Lawler, Sean, Schiff, David, Soffietti, Riccardo, Aldape, Kenneth

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 67 KB

english, 2017

86

Highlights from the Literature

Schiff, David, Soffietti, Riccardo, Huse, Jason, Lawler, Sean, Hegi, Monika, Aldape, Kenneth

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 65 KB

english, 2017

87

miR451 and AMPK Mutual Antagonism in Glioma Cell Migration and Proliferation: A Mathematical Model

Kim, Yangjin, Roh, Soyeon, Lawler, Sean, Friedman, Avner, Castro, Maria G.

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 800 KB

english, 2011

88

ABT-263 Enhances Sensitivity to Metformin and 2-Deoxyglucose in Pediatric Glioma by Promoting Apoptotic Cell Death

Levesley, Jane, Steele, Lynette, Taylor, Claire, Sinha, Priyank, Lawler, Sean E., Shellman, Yiqun G.

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 5.88 MB

english, 2013

89

Strategies of Eradicating Glioma Cells: A Multi-Scale Mathematical Model with MiR-451-AMPK-mTOR Control

Kim, Yangjin, Powathil, Gibin, Kang, Hyunji, Trucu, Dumitru, Kim, Hyeongi, Lawler, Sean, Chaplain, Mark, Najbauer, Joseph

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 5.96 MB

english, 2015

90

IMMU-10. EXPRESSION OF PD-L2, IN GLIOBLASTOMA; IMPLICATIONS AS A BIOMARKER FOR IMMUNOTHERAPY

Ricklefs, Franz, Hayes, Josie, Speranza, Maria Carmela, Krenzlin, Harald, Costello, Joseph, Freeman, Gordon J, Westphal, Manfred, Lamszus, Katrin, Chiocca, E Antonio, Lawler, Sean E

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 49 KB

english, 2017

91

Cover image, Volume 31 Issue 10

Schregel, Katharina, Nazari, Navid, Nowicki, Michal O., Palotai, Miklos, Lawler, Sean E., Sinkus, Ralph, Barbone, Paul E., Patz, Samuel

Journal:

NMR in Biomedicine

Année:

2018

Fichier:

PDF, 407 KB

2018

92

Arming an oncolytic herpes simplex virus Type 1 with a single chain fragment variable antibody against PD-1 for experimental glioblastoma therapy.

Passaro, Carmela, Alayo, Quazim, DeLaura, Isabel, McNulty, John J, Grauwet, Korneel, Ito, Hirotaka, Bhaskaran, Vivek, Mineo, Marco, lawler, sean e, Shah, Khalid, Speranza, Maria C, Goins, William F, M

Journal:

Clinical Cancer Research

Année:

2018

Langue:

english

Fichier:

PDF, 3.28 MB

english, 2018

93

Role of extracellular matrix and microenvironment in regulation of tumor growth and LAR-mediated invasion in glioblastoma

Kim, Yangjin, Kang, Hyunji, Powathil, Gibin, Kim, Hyeongi, Trucu, Dumitru, Lee, Wanho, Lawler, Sean, Chaplain, Mark, Wodarz, Dominik

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 7.81 MB

english, 2018

94

The multiple protective roles and molecular mechanisms of melatonin and its precursor N-acetylserotonin, in targeting brain injury and liver damage and in maintaining bone health

Luo, Chengliang, Yang, Qiang, Liu, Yuancai, Zhou, Shuanhu, Jiang, Jiying, Reiter, Russel J., Bhattacharya, Pallab, Cui, Yongchun, Yang, Hongwei, Ma, He, Yao, Jiemin, Lawler, Sean E., Zhang, Xinmu, Fu,

Journal:

Free Radical Biology and Medicine

Année:

2018

Langue:

english

Fichier:

PDF, 1.54 MB

english, 2018

95

Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Bergmann, Sonja, Lawler, Sean E., Qu, Yuan, Fadzen, Colin M., Wolfe, Justin M., Regan, Michael S., Pentelute, Bradley L., Agar, Nathalie Y. R., Cho, Choi-Fong

Journal:

Nature Protocols

Année:

2018

Langue:

english

Fichier:

PDF, 3.15 MB

english, 2018

96

DDIS-12. A FACILE, ROBUST AND PREDICTIVE IN VITRO BLOOD-BRAIN-BARRIER MODEL FOR HIGH-THROUGHPUT SCREENING AND DISCOVERY OF BRAIN-PENETRATING AGENTS

Cho, Choi-Fong, Wolfe, Justin, Fazden, Colin, Hornburg, Kalvis, Chiocca, E. Antonio, Pentelute, Bradley, Lawler, Sean E.

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 124 KB

english, 2016

97

Novel non-nucleotidic STING agonists for cancer immunotherapy

Berger, Gilles, Lawler, Sean E

Journal:

Future Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 172 KB

english, 2018

98

Pharmacological Modulation of the STING Pathway for Cancer Immunotherapy

Berger, Gilles, Marloye, Mickaël, Lawler, Sean E.

Journal:

Trends in Molecular Medicine

Année:

2019

Fichier:

PDF, 3.95 MB

2019

99

IMMU-28. DEFINING MOLECULAR MECHANISMS OF RESISTANCE TO GLIOBLASTOMA (GBM) IMMUNITY USING A NOVEL CRISPR/CAS9 IN VIVO LOSS-OF-FUNCTION SCREENING PLATFORM

Neagu, Martha R, Speranza, Maria Carmela, Manguso, Robert T, Lawler, Sean E, Freeman, Gordon J, Doench, John, Sharpe, Arlene H, Haining, W Nicholas

Journal:

Année:

2017

Fichier:

PDF, 86 KB

2017

100

Proteomic Analysis Implicates Vimentin in Glioblastoma Cell Migration

Nowicki, Michal, Hayes, Josie, Chiocca, E., Lawler, Sean

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 3.26 MB

english, 2019