Jörg Huwyler : rechercher sur Z-Library

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51

Interaction of the antiviral drug telaprevir with renal and hepatic drug transporters

Annett Kunze, Jörg Huwyler, Gian Camenisch, Heike Gutmann

Journal:

Biochemical Pharmacology

Année:

2012

Langue:

english

Fichier:

PDF, 597 KB

english, 2012

52

Drug Transport to Brain with Targeted Liposomes

Anita Schnyder, Jörg Huwyler

Journal:

Neurotherapeutics

Année:

2005

Langue:

english

Fichier:

PDF, 216 KB

english, 2005

53

Computational Prediction of Blood-Brain Barrier Permeability Using Decision Tree Induction

Suenderhauf, Claudia, Hammann, Felix, Huwyler, Jörg

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 269 KB

english, 2012

54

Drug interaction potential of resveratrol

Detampel, Pascal, Beck, Mareike, Krähenbühl, Stephan, Huwyler, Jörg

Journal:

Drug Metabolism Reviews

Année:

2012

Langue:

english

Fichier:

PDF, 787 KB

english, 2012

55

In Vitro - In Vivo Extrapolation Method to Predict Human Renal Clearance of Drugs

Kunze, Annett, Huwyler, Jörg, Poller, Birk, Gutmann, Heike, Camenisch, Gian

Journal:

Journal of Pharmaceutical Sciences

Année:

2014

Langue:

english

Fichier:

PDF, 729 KB

english, 2014

56

Compaction of functionalized calcium carbonate, a porous and crystalline microparticulate material with a lamellar surface

Stirnimann, Tanja, Atria, Susanna, Schoelkopf, Joachim, Gane, Patrick A.C., Alles, Rainer, Huwyler, Jörg, Puchkov, Maxim

Journal:

International Journal of Pharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2014

57

Drug loading into porous calcium carbonate microparticles by solvent evaporation

Preisig, Daniel, Haid, David, Varum, Felipe J.O., Bravo, Roberto, Alles, Rainer, Huwyler, Jörg, Puchkov, Maxim

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.71 MB

english, 2014

58

A cell-based, multiparametric sensor approach characterises drug-induced cytotoxicity in human liver HepG2 cells

Seeland, Swen, Török, Michael, Kettiger, Helene, Treiber, Alexander, Hafner, Mathias, Huwyler, Jörg

Journal:

Toxicology in Vitro

Année:

2013

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2013

59

Indocyanine green loaded biocompatible nanoparticles: Stabilization of indocyanine green (ICG) using biocompatible silica-poly(ε-caprolactone) grafted nanocomposites

Schönbächler, Andrea, Glaied, Olfa, Huwyler, Jörg, Frenz, Martin, Pieles, Uwe

Journal:

Journal of Photochemistry and Photobiology A: Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2013

60

Efficacy and pharmacokinetics of OZ78 and MT04 against a natural infection with Fasciola hepatica in sheep

Meister, Isabel, Duthaler, Urs, Huwyler, Jörg, Rinaldi, Laura, Bosco, Antonio, Cringoli, Giuseppe, Keiser, Jennifer

Journal:

Veterinary Parasitology

Année:

2013

Langue:

english

Fichier:

PDF, 930 KB

english, 2013

61

Brain Drug Delivery of Small Molecules Using Immunoliposomes

Jorg Huwyler, Dafang Wu and William M. Pardridge

Journal:

Proceedings of the National Academy of Sciences

Année:

1996

Langue:

english

Fichier:

PDF, 1.23 MB

english, 1996

62

High-throughput viscosity measurement using capillary electrophoresis instrumentation and its application to protein formulation

Allmendinger, Andrea, Dieu, Le-Ha, Fischer, Stefan, Mueller, Robert, Mahler, Hanns-Christian, Huwyler, Jörg

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2014

Langue:

english

Fichier:

PDF, 801 KB

english, 2014

63

Endocytosis and Transcytosis of an Immunoliposome-Based Brain Drug Delivery System

Cerletti, Andrin, Drewe, Jürgen, Fricker, Gert, Eberle, Alex, Huwyler, Jörg

Journal:

Journal of Drug Targeting

Année:

2000

Langue:

english

Fichier:

PDF, 1.58 MB

english, 2000

64

Polymersomes conjugated to 83-14 monoclonal antibodies: Invitro targeting of brain capillary endothelial cells

Dieu, Le-Ha, Wu, Dalin, Palivan, Cornelia G., Balasubramanian, Vimalkumar, Huwyler, Jörg

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Année:

2014

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2014

65

Human cytokines activate JAK-STAT signaling pathway in porcine ocular tissue

Fasler-Kan, Elizaveta, Barteneva, Natasha S., Ketterer, Sylvia, Wunderlich, Kerstin, Reschner, Anca, Nurzhanova, Asil, Flammer, Josef, Huwyler, Jörg, Meyer, Peter

Journal:

Xenotransplantation

Année:

2013

Langue:

english

Fichier:

PDF, 511 KB

english, 2013

66

Stable human brain microvascular endothelial cell line retaining its barrier-specific nature independent of the passage number

Sano, Yasuteru, Kashiwamura, Yoko, Abe, Masaaki, Dieu, Le-Ha, Huwyler, Jörg, Shimizu, Fumitaka, Haruki, Hiroyo, Maeda, Toshihiko, Saito, Kazuyuki, Tasaki, Ayako, Kanda, Takashi

Journal:

Clinical and Experimental Neuroimmunology

Année:

2013

Langue:

english

Fichier:

PDF, 701 KB

english, 2013

67

Targeting of daunomycin using biotinylated immunoliposomes: Pharmacokinetics, tissue distribution and in vitro pharmacological effects

Schnyder, Anita, Krähenbühl, Stephan, Drewe, Jürgen, Huwyler, Jörg

Journal:

Journal of Drug Targeting

Année:

2005

Langue:

english

Fichier:

PDF, 318 KB

english, 2005

68

By-passing of P-glycoprotein Using Immunoliposomes

Huwyler, Jörg, Cerletti, Andrin, Fricker, Gert, Eberle, Alex N., Drewe, Jürgen

Journal:

Journal of Drug Targeting

Année:

2002

Langue:

english

Fichier:

PDF, 1.40 MB

english, 2002

69

Treatment of Large Solid Tumors in Mice with Daunomycin-Loaded Sterically Stabilized Liposomes

Golden, Pamela L., Huwyler, JÖRg, Pardridge, William M.

Journal:

Année:

1998

Langue:

english

Fichier:

PDF, 693 KB

english, 1998

70

Marker-ion analysis for quantification of mucoadhesivity of microparticles in particle-retention assays

Preisig, Daniel, Weingartner, Michael, Varum, Felipe J.O., Bravo, Roberto, Alles, Rainer, Huwyler, Jörg, Puchkov, Maxim

Journal:

International Journal of Pharmaceutics

Année:

2015

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2015

71

Biocompatible Polymer–Peptide Hybrid-Based DNA Nanoparticles for Gene Delivery

Witzigmann, Dominik, Wu, Dalin, Schenk, Susanne H., Balasubramanian, Vimalkumar, Meier, Wolfgang, Huwyler, Jörg

Journal:

ACS Applied Materials & Interfaces

Année:

2015

Langue:

english

Fichier:

PDF, 3.18 MB

english, 2015

72

LC–MS/MS method for the determination of two metabolites of tribendimidine, deacylated amidantel and its acetylated metabolite in plasma, blood and dried blood spots

Duthaler, Urs, Keiser, Jennifer, Huwyler, Jörg

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2015

Langue:

english

Fichier:

PDF, 1.61 MB

english, 2015

73

Application of the extended clearance concept classification system (ECCCS) to predict the victim drug-drug interaction potential of statins

Kunze, Annett, Poller, Birk, Huwyler, Jörg, Camenisch, Gian

Journal:

Drug Metabolism and Personalized Therapy

Année:

2015

Langue:

english

Fichier:

PDF, 722 KB

english, 2015

74

Drug targeting using OX7-immunoliposomes: Correlation between Thy1.1 antigen expression and tissue distribution in the rat

Tuffin, Gérald, Huwyler, Jörg, Waelti, Ernst, Hammer, Caroline, Marti, Hans-Peter

Journal:

Journal of Drug Targeting

Année:

2008

Langue:

english

Fichier:

PDF, 527 KB

english, 2008

75

Induction of Cytochrome P450 3A4 and P-Glycoprotein by the Isoxazolyl- Penicillin Antibiotic Flucloxacillin

Huwyler, Jorg, Wright, Matthew, Gutmann, Heike, Drewe, Juergen

Journal:

Current Drug Metabolism

Année:

2006

Langue:

english

Fichier:

PDF, 189 KB

english, 2006

76

Oxantel Pamoate–Albendazole for Trichuris trichiura Infection

Speich, Benjamin, Ame, Shaali M., Ali, Said M., Alles, Rainer, Huwyler, Jörg, Hattendorf, Jan, Utzinger, Jürg, Albonico, Marco, Keiser, Jennifer

Journal:

New England Journal of Medicine

Année:

2014

Langue:

english

Fichier:

PDF, 643 KB

english, 2014

77

Formation of Lipid and Polymer Based Gold Nanohybrids Using a Nanoreactor Approach

Witzigmann, Dominik, Sieber, Sandro, Porta, Fabiola, Grossen, Philip, Bieri, Andrej, Strelnikova, Natalja, Pfohl, Thomas, Prescianotto-Baschong, Cristina, Huwyler, Jörg

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.87 MB

english, 2015

78

Comparative safety evaluation of silica-based particles

Kettiger, Helene, Karaman, Didem Sen, Schiesser, Laura, Rosenholm, Jessica M., Huwyler, Jörg

Journal:

Toxicology in Vitro

Année:

2015

Langue:

english

Fichier:

PDF, 1.49 MB

english, 2015

79

Efficacy and safety of oxantel pamoate in school-aged children infected with Trichuris trichiura on Pemba Island, Tanzania: a parallel, randomised, controlled, dose-ranging study

Moser, Wendelin, Ali, Said M, Ame, Shaali M, Speich, Benjamin, Puchkov, Maxim, Huwyler, Jörg, Albonico, Marco, Hattendorf, Jan, Keiser, Jennifer

Journal:

The Lancet Infectious Diseases

Année:

2015

Langue:

english

Fichier:

PDF, 362 KB

english, 2015

80

Comparative Evaluation of Two Methods for Preparative Fractionation of Proteinaceous Subvisible Particles—Differential Centrifugation and FACS

Boll, Björn, Folzer, Emilien, Finkler, Christof, Huwyler, Jörg, Mahler, Hanns-Christian, Schmidt, Roland, Koulov, Atanas V.

Journal:

Pharmaceutical Research

Année:

2015

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2015

81

New IVIVE method for the prediction of total human clearance and relative elimination pathway contributions from in vitro hepatocyte and microsome data

Riede, Julia, Poller, Birk, Umehara, Ken-ichi, Huwyler, Jörg, Camenisch, Gian

Journal:

European Journal of Pharmaceutical Sciences

Année:

2016

Langue:

english

Fichier:

PDF, 754 KB

english, 2016

82

ATP-induced cellular stress and mitochondrial toxicity in cells expressing purinergic P2X7 receptor

Seeland, Swen, Kettiger, Hélène, Murphy, Mark, Treiber, Alexander, Giller, Jasmin, Kiss, Andrea, Sube, Romain, Krähenbühl, Stephan, Hafner, Mathias, Huwyler, Jörg

Journal:

Pharmacology Research & Perspectives

Année:

2015

Langue:

english

Fichier:

PDF, 1022 KB

english, 2015

83

Pediatric Dispersible Tablets: a Modular Approach for Rapid Prototyping

Buck, Jonas, Huwyler, Jörg, Kühl, Peter, Dischinger, Angela

Journal:

Pharmaceutical Research

Année:

2016

Langue:

english

Fichier:

PDF, 940 KB

english, 2016

84

Secreted Matrix Metalloproteinase-9 of Proliferating Smooth Muscle Cells as a Trigger for Drug Release from Stent Surface Polymers in Coronary Arteries

Gliesche, Daniel G., Hussner, Janine, Witzigmann, Dominik, Porta, Fabiola, Glatter, Timo, Schmidt, Alexander, Huwyler, Jörg, Meyer zu Schwabedissen, Henriette E.

Journal:

Molecular Pharmaceutics

Année:

2016

Langue:

english

Fichier:

PDF, 3.70 MB

english, 2016

85

Histamine-3 Receptor Inverse Agonists for the Treatment of Obesity: Validation of the Target and Identification of Novel Series

Pierson, Pascale David, Freichel, Christian, Gatti-Mac Arthur, Silvia, Hertel, Cornelia, Huwyler, Jörg, Mohr, Peter, Nakagawa, Toshito, Nettekoven, Matthias, Plancher, Jean-Marc, Raab, Susanne, Richte

Journal:

CHIMIA International Journal for Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 255 KB

english, 2009

86

Interactions between silica nanoparticles and phospholipid membranes

Kettiger, Helene, Québatte, Gabriela, Perrone, Barbara, Huwyler, Jörg

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Année:

2016

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2016

87

Variable asialoglycoprotein receptor 1 expression in liver disease: Implications for therapeutic intervention

Witzigmann, Dominik, Quagliata, Luca, Schenk, Susanne H., Quintavalle, Cristina, Terracciano, Luigi M., Huwyler, Jörg

Journal:

Hepatology Research

Année:

2016

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2016

88

Selective Oxidation of Methionine and Tryptophan Residues in a Therapeutic IgG1 Molecule

folzer, Emilien, diepold, Katharina, bomans, Katrin, finkler, Christof, schmidt, Roland, bulau, Patrick, huwyler, Jörg, mahler, Hanns-christian, koulov, Atanas V.

Journal:

Journal of Pharmaceutical Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 603 KB

english, 2015

89

CombiCap: A novel drug formulation for the basel phenotyping cocktail

Camblin, Marine, Berger, Benjamin, Haschke, Manuel, Krähenbühl, Stephan, Huwyler, Jörg, Puchkov, Maxim

Journal:

International Journal of Pharmaceutics

Année:

2016

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2016

90

Targeting of skeletal muscle in vitro using biotinylated immunoliposomes

SCHNYDER, Anita, KRÄHENBÜHL, Stefan, TÖRÖK, Michael, DREWE, Jürgen, HUWYLER, Jörg

Journal:

Biochemical Journal

Année:

2004

Langue:

english

Fichier:

PDF, 173 KB

english, 2004

91

Pharmacokinetics of the antischistosomal lead OZ418 in uninfected mice determined by LC-MS/MS

Leonidova, Anna, Vargas, Mireille, Huwyler, Jörg, Keiser, Jennifer

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 1.15 MB

english, 2016

92

Isolation of multiantennary N-glycans from glycoproteins for hepatocyte specific targeting via the asialoglycoprotein receptor

Witzigmann, Dominik, Detampel, Pascal, Porta, Fabiola, Huwyler, Jörg

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 454 KB

english, 2016

93

Single-Ascending-Dose Pharmacokinetic Study of Tribendimidine in Opisthorchis viverrini-Infected Patients

Duthaler, Urs, Sayasone, Somphou, Vanobbergen, Fiona, Penny, Melissa A., Odermatt, Peter, Huwyler, Jörg, Keiser, Jennifer

Journal:

Antimicrobial Agents and Chemotherapy

Année:

2016

Langue:

english

Fichier:

PDF, 671 KB

english, 2016

94

Polymersomes containing quantum dots for cellular imaging

Huwyler, Jörg, Camblin, Marine, Detampel, Pascal, Kettiger, Helene, Wu, Dalin, Balasubramanian, Vimalkumar

Journal:

International Journal of Nanomedicine

Année:

2014

Langue:

english

Fichier:

PDF, 2.78 MB

english, 2014

95

Extensive Chemical Modifications in the Primary Protein Structure of IgG1 Subvisible Particles Are Necessary for Breaking Immune Tolerance

Boll, Björn, Bessa, Juliana, Folzer, Emilien, Ríos Quiroz, Anacelia, Schmidt, Roland, Bulau, Patrick, Finkler, Christof, Mahler, Hanns-Christian, Huwyler, Jörg, Iglesias, Antonio, Koulov, Atanas V.

Journal:

Molecular Pharmaceutics

Année:

2017

Langue:

english

Fichier:

PDF, 1.64 MB

english, 2017

96

Assessing the Risk of Drug-Induced Cholestasis Using Unbound Intrahepatic Concentrations

Riede, Julia, Poller, Birk, Huwyler, Jörg, Camenisch, Gian

Journal:

Drug Metabolism and Disposition

Année:

2017

Langue:

english

Fichier:

PDF, 3.33 MB

english, 2017

97

Immobilization of Enzymes on PLGA Sub-Micrometer Particles by Crosslinked Layer-by-Layer Deposition

Sieber, Sandro, Siegrist, Stefan, Schwarz, Stéphanie, Porta, Fabiola, Schenk, Susanne H., Huwyler, Jörg

Journal:

Macromolecular Bioscience

Année:

2017

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2017

98

Efficacy of moxidectin versus ivermectin against Strongyloides stercoralis infections: a randomized controlled non-inferiority trial

Barda, Beatrice, Sayasone, Somphou, Phongluxa, Khampheng, Xayavong, Syda, Keoduangsy, Khonsavanh, Odermatt, Peter, Puchkov, Maxim, Huwyler, Jörg, Hattendorf, Jan, Keiser, Jennifer

Journal:

Clinical Infectious Diseases

Année:

2017

Langue:

english

Fichier:

PDF, 294 KB

english, 2017

99

Current In Vitro Methods to Determine Hepatic Kp uu : A Comparison of Their Usefulness and Limitations

Riede, Julia, Camenisch, Gian, Huwyler, Jörg, Poller, Birk

Journal:

Journal of Pharmaceutical Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2017

100

Characterization of new Functionalized Calcium Carbonate-Polycaprolactone Composite Material for Application in Geometry-constrained Drug Release Formulation Development

Wagner-Hattler, Leonie, Schoelkopf, Joachim, Huwyler, Jörg, Puchkov, Maxim

Journal:

Drug Development and Industrial Pharmacy

Année:

2017

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2017